September 8, 2006

Dapoxetine for premature ejaculation

Dapoxetine

Dapoxetine, an SSRI patented by ALZA pharmaceuticals is showing some real promise combatting premature ejaculation. Dapoxetine, of course, has been around for a little while, though it's not available yet by prescription. (It's currently in Phase III trials.)

The analysis involved over 2600 men with moderate to severe premature ejaculation and their partners. Patients were randomly assigned to receive placebo (870), 30 mg dapoxetine (874), or 60 mg dapoxetine (870) and were instructed to take a dose 1-3 hours before sexual intercourse. On average, at the start of the study, the men ejaculated under a minute after penetration. The researchers found that after 12 weeks the time to ejaculation was 1.75 minutes for placebo, 2.78 minutes for 30 mg dapoxetine, and 3.32 minutes for 60 mg dapoxetine.

Not being a lifestyle drug player-hater, I'm happy to see some progress being made on premature ejaculation. Count me as one person who had no idea it was so common. As with erectile dysfunction, I'm happy that these lifestyle afflictions — which I'm sure are traumatic for these men and their partners — are treatable. By the same token, I'm glad that we've reached a point in time where things like erectile dysfunction and premature ejaculation are now treatable. Some would have us go back to the dark ages ignoring these "umimportant" problems, but I think it's nice that we are in a society that can afford to do life-saving research and life-enriching research simultaneously. Though, like many other medical professionals, I sometimes wonder if one is being done at the expense of the other.

[Image from ScienceBase]

| 10:11 pm |

16 Comments

  1. Hi, I have heard that this drug (Dapoxetine) has finally been approved by the FDA. I really wonder how soon we can expect to see that it is commercially available to public. I am looking forward to trying it.

    Respectfully,
    Selahattin Genc

    Comment by Selahattin Genc — October 31, 2006 @ 4:04 pm

  2. Well, it hasn't been approved yet, but approval is supposedly near…

    Comment by RJS — October 31, 2006 @ 11:32 pm

  3. It's a shame but it's not approved
    http://dapoxetineapproval.com/
    greetings Eduard from the netherlands

    Comment by Eduard — November 6, 2006 @ 5:11 pm

  4. so will dapoxetine be available to public even if its not approved??

    Comment by omer — November 9, 2006 @ 5:04 pm

  5. It'll be unavailable in the US until it's approved by the FDA.

    Comment by RJS — November 9, 2006 @ 6:08 pm

  6. why is the FDA delaying the approval of this drug and is it available in other countries if not in the US??

    Comment by omer — November 10, 2006 @ 3:57 am

  7. Please let me know when available!

    Comment by Tom O Brien — November 10, 2006 @ 1:55 pm

  8. Is there any other drug which can be taken to cure (PE)and has effective results??

    Comment by omer — November 15, 2006 @ 6:10 am

  9. why they dont let peapole have hat nature offered them

    Comment by fouz — November 30, 2006 @ 6:56 pm

  10. where can this drug be obtained. Its marketability is unbelievable

    Comment by jason — January 2, 2007 @ 5:21 am

  11. [...] One of my most popular posts here at OnThePharm (and most commented on) is my "Dapoxetine for premature ejaculation" entry, with many commenters wondering where and when it will be available. (I have no idea — that's up to the FDA, sorry.) When and if dapoxetine becomes available, I can see it being marketed in much the same way that Viagra has been. And initially it'll be treated by the public as "Tee hee, if you need this, you're less than a man." And slowly PE will become a socially-acceptable thing to talk about, and men will be looked down on less because of the increased awareness. [...]

    Pingback by Topical anesthetic for premature ejaculation :: OnThePharm — January 24, 2007 @ 2:49 pm

  12. cheaptraintickets

    Comment by cheapskivacations — February 22, 2007 @ 4:54 am

  13. I would like to know where I can get it from? Anyone know?

    Comment by Debbie — March 1, 2007 @ 12:28 pm

  14. Just checking on when there might be some new news on when is it coming back up to the FDA approval?? and I heared that it was already being sold in India, is that true and will they ship it overseas?

    Comment by Stephen — April 17, 2007 @ 1:11 pm

  15. I managed to get information from a clinic in Zhongkang Weiye Biological Science & Technology Co., Ltd Shanghai

    Xitai Road No.237, Xuhui Area (ECUST Park), Shanghai, China

    They said it would cost approx $50 inc delivery for 30 tabs. I havent yet ordered as not quite sure of the authencity of it. Has anyone come across this clinic?

    Comment by Debbie — April 18, 2007 @ 3:05 pm

  16. Zhongkang Weiye Biological Science & Technology Co. >>

    Yea, I would avoid that like the plague.

    Comment by Ziggy — April 19, 2007 @ 8:54 pm

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