levitra kaufen ohne rezept levitra billig kaufen viagra türkei kaufen original cialis bestellen cialis generika eu cialis preis deutschland cialis generika online kaufen cialis 5mg rezeptfrei viagra tschechien cialis 10mg preis levitra preiswert generic tadalafil generika levitra schweiz cialis bestellen ohne rezept preço de viagra cialis kaufen österreich preisvergleich levitra viagra generika nebenwirkung viagra bestellen schweiz viagra kaufen in der schweiz cialis generika apotheke nebenwirkungen cialis generika viagra tabletten teilen viagra generika ratiopharm preisvergleich cialis viagra tabletten kaufen pfizer viagra kaufen potenzmittel cialis kaufen levitra per nachnahme cialis holland rezeptfrei cialis rezept viagra ersatz viagra günstig kaufen viagra kaufen privat sildenafil indien viagra rezeptfrei kaufen viagra nachnahme pillen viagra viagra generika online kaufen cialis ohne rezept cialis rezeptpflicht generika levitra viagra rezeptfrei bestellen generika tadalafil cialis preis apotheke cialis 5mg kaufen cialis per nachnahme bestellen cialis in österreich kaufen viagra kaufen in wien viagra per nachnahme bestellen viagra deutschland kaufen levitra 20mg filmtabletten sildenafil rezeptfrei cialis in holland cialis kaufen in deutschland versandapotheke cialis viagra per nachnahme kaufen cialis 5mg preis cialis kaufen deutschland internetapotheke cialis günstig viagra cialis generika schweiz cialis generika aus deutschland vardenafil rezeptfrei viagra online kaufen de viagra im internet kaufen cialis rezeptfrei aus deutschland sildenafil bestellen comprar viagra em portugal cialis billiger viagra generika aus deutschland viagra kaufen at cialis kaufen paypal generika viagra kaufen vardenafil bestellen viagra aus indien generika viagra viagra pillenmaster viagra kaufen in berlin viagra kaufen wo viagra alternativ filmtabletten cialis levitra holland viagra im internet bestellen strafbar cialis tabletten tadalafil preisvergleich cialis kaufen billig levitra ohne rezept kaufen viagra kaufen mit rezept cialis generika preiswert viagra alternativen viagra kaufen günstig viagra filmtabletten viagra kaufen in hamburg viagra rezeptfrei günstig levitra günstig kaufen cialis tadalafil kaufen cialis preise türkei cialis generika preisvergleich viagra kaufen in deutschland viagra kaufen paypal viagra woman kaufen sildenafil ohne rezept tadalafil 20mg kaufen cialis 10 mg rezeptfrei viagra einzeln bestellen tadalafil apotheke cialis rezeptfrei in holland pille viagra levitra preço levitra online bestellen levitra apotheke viagra versand levitra generika preisvergleich erectie middelen viagra ersatzmittel cialis generika rezeptfrei viagra pillendienst viagra schweiz rezeptfrei cialis preço viagra preis österreich cialis 5mg filmtabletten preisvergleich niederlande cialis cialis rezeptfrei kaufen cialis berlin viagra rezeptfrei schweiz tabletten cialis cialis im internet bestellen levitra generika nebenwirkungen cialis versand erfahrungen viagra generika viagra generika wirkung viagra generika kaufen viagra usa kaufen cialis in deutschland kaufen cialis rezeptfrei schweiz viagra kostengünstig viagra zu kaufen cialis im preisvergleich cialis eds apotheke viagra ou similar cialis tadalafil bestellen viagra günstig ohne rezept cialis aus indien viagra online versand viagra generika erfahrungen viagra zum kaufen sildenafil preise rezept cialis viagra kaufen schweiz viagra 50 mg kaufen
August 2, 2007

Suckin' on the ol' sewer pipe

This post was originally going to entitled Metronidazole: a haiku. Alas, I suck at writing haikus. Yes, dear reader, there is more to a good haiku than 17 syllables. By the way, did you ever marvel at the irony of learning haiku in an English class? I always did, but my teachers were always more interested in teaching it than arguing about it. I was always of the mind that arguing > haiku, but they always disagreed.

That's probably they were English teachers in the first place.

Oh, right. This is a pharmacy blog, so back to pharmacy. Specifically to metronidazole AKA Flagyl AKA Shai'tan, AKA Lucifer, the Morning Star himself.

The gods have seen fit to curse me several times throughout my life with the scourge that is metronidazole. I take it (along with a fluouroquinolone) when my Crohn's flares up, and it works well. Thus far, I have successfully avoided taking any immunomodulators or steroids. But metronidazole has some totally rad side effects. And by "totally rad" I mean "the worst ever."

First is the taste. It comes in three parts. The first is that awesome nastiness that'll make you gag as soon as it hits your tongue if you're not ready for it. Then there's the lingering powdery residue that no amount of food or orange juice can seem to scrub away. The third part is the full-blown taste perversion that comes a day or so later: that dull throb that wears you down slowly instead of the sharp pain that makes you gasp. That taste that makes you feel as though you're sucking on a sewer pipe while your gums bleed profusely into the fetid mess each and every time you take a breath.

Bottoms up, friend. It's only day 2 of 10.

Then there's the smell perversion, where everything that's good and sweet in this world turns to ash and dust. Coffee. Pineapple. Chocolate. Forget about sticking your nose near any of it. Then there's the urine which looks to be made of equal parts blood and urine. Which itself smells like liquid death. (Asparagus has got nothing on Flagyl-piss.) You look in the toilet afterwards and expect to see bits of protein next time as your kidney slowly liquefies itself.

Some say I should count myself fortunate that I don't seem to experience any psych side effects like depression or nightmares. But I think I'd take nightmares over constant sewer mouth.

Tomorrow marks the last day of a ten day course of this shit, and it can't come soon enough. The side effects seem to intensify with each round. Or is it that I become less patient? Thankfully Christmas only seems to come once a year so far. The only thing that helps is ice cream. Lots and lots of ice cream so I can freeze my mouth and get ten blessed minutes of nothing.

I think if I had mortal enemies, I'd provide them with a lifetime supply of metronidazole, 500mg TID to be taken with only a swallow of water each time.

If you enjoyed this, or have taken Flagyl/metronidazole in the past, you may enjoy this entry about the (lack of) alcohol+Flagyl reaction.

View Comments | 11:30 pm |
  • Rick Schlauch
    Drink Rick Schlauch Beer and Chips and you will shit your way to happiness. No doubt!!!
  • T.C.
    Fecal bacteriotherapy
    Fecal bacteriotherapy, a procedure related to probiotic research, has been suggested as a potential cure for the disease. It involves infusion of bacterial flora acquired from the feces of a healthy donor in an attempt to reverse bacterial imbalance responsible for the recurring nature of the infection. It has a success rate of nearly 95% according to some sources.[31][32][33]

    Ah yes as I am sure would be most preferred over Flagyl
  • T.C.
    OK Day 7 and last was yesterday. Definite sewer mouth taste. Liquid stool for 8 days now. Maybe soon I won't need to carry an extra pair of pants just in case. Got lucky have been able to get to the potty so far. This rotten fungal pasty funk in my mouth is the worst. I started to wonder if my lungs were infested with rot. Only puked a few times, not to big of a deal. And surprise, surprise got fed up and drank alcohol on day 6 no problems. Come to find out it's suppose to be akin to Antabuse , I was feeling pretty good with a few drinks in me. I just brushed like crazy with baking soda and I sware it was foaming or tingling as if I had an acidic mouth.
  • Prickle
    I am on day two of Flagyl and wasn't given any warnings about side effects by my doctor. Was slightly worried about my piss looking like blood, nausea, etc. Am less worried now! Thanks!
  • Jessica
    Everything said in this article is absolutely true. You had me laughing the whole way through! I'm on about day 7, and I cannot wait until all those little white pills of torture are gone... My favorite part was when you wrote : "Then there's the urine which looks to be made of equal parts blood and urine. Which itself smells like liquid death. (Asparagus has got nothing on Flagyl-piss.) You look in the toilet afterwards and expect to see bits of protein next time as your kidney slowly liquefies itself." How true is that?? Well, although this course of medicine is disgusting, I'm glad I'm not the only one going through it. Hopefully, I will never EVER get Cdiff again. (This medicine just may be worse than the problem it's treating)
  • RJS
    I just stumbled onto this site while surfing. After 10 days, I’m up from the sewers and back to sunshine. I was starting to wonder if that sticky white residue on my tongue would ever disappear. I’m counting down the hours to have a nice drinky drink too. Metal mouth is gone and CDiff too!


    You can drink while taking Flagyl.
  • EJA
    I just stumbled onto this site while surfing. After 10 days, I'm up from the sewers and back to sunshine. I was starting to wonder if that sticky white residue on my tongue would ever disappear. I'm counting down the hours to have a nice drinky drink too. Metal mouth is gone and CDiff too!
  • RJS
    Interesting thought. I wonder if you could substitute metronidazole with something in the rifampin family. Maybe a little isoniazid as well.

    Neither of those options really appeals to me, but if I had to do six months of abx and then never have to worry about Crohn's again, I would be on that shit in a heartbeat.

    I'll have to look into the literature. But next up... "Alcohol and Metronidazole: Where're the data, dood?" Gotta love when conventional wisdom is anything but.
  • Kirsten
    There is a theory out there that some Crohn's disease is actually a Mycobacteria paratuberculosis infection, similar to Johne's disease in animals. Hence, a (prolonged - Mycobacteria aren't easy to kill) course of antibiotics can be an effective cure.
  • RJS
    Yeah I had a friend with CDiff that would vomit if he took it. Strangely enough, I can take it on an empty stomach and be just fine, which boggles everyone's mind. Have been able to, ever since I accidentally took it on an empty stomach and just battled through the resulting GI distress (was in the middle of class). It's almost like a bizarre sort of immunity, and ever since, it doesn't bother me.

    I almost wish I *couldn't* take it. Almost.

    But it really does seem to help. I wish they could elucidate the mechanism of action for the FQ-flagyl combo that quells the inflammation.
  • CardioNP
    Ah, be glad you can take the stuff. Needed to take Flagyl as part of pre-op prep - after taking bowel prep.
    Had severe GI distress followed by hematemesis.
    Ended up in the ER and my surgery was cancelled.
    After my experiences, I'll never take it again.
blog comments powered by Disqus

google

couk