Viagra > Cialis for fertility purposes
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I read something new the other day that I thought was interesting, and potentially important to prescribers treating couples trying to conceive:
Dr. Giorgio Pomara and colleagues at the University of Pisa in Rome, administered a single 50 mg dose of sildenafil or 20 mg of tadalafil to 18 young infertile men in a randomized, double-blind crossover study with a two-week washout period between treatment arms.
Semen samples collected one to two hours after each treatment. The investigators report that sperm progressive motility significantly increased with sildenafil from 28.5% at baseline to 37.0% after treatment. Tadalafil significantly decreased sperm progressive motility from 28.5% at baseline to 21.5% after treatment.
Cialis decreased sperm motility by 7%, whereas Viagra increased it by 8.5%. That's quite a difference, and I suspect it's clinically significant for couples looking to conceive, where erectile dysfunction is common.
Fertil Steril 2007;88:860-865.
[tags]Viagra, Cialis, fertility[/tags]
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